Grignard Reaction

The Grignard reception Synthesis of triphenylmethanol tease Wilson Chem 443-003 January 1,2012-February 7,2012 Introduction In this experiment we synthesized triphenylmethanol from a Grignard reagent and an ester. To form triphenylmethanol we reacted methyl benzoate with phenylmagnesium bromide. Reaction Scheme: Theory An organo alloylic compound is an pilot film compound that contains a blow-metallic bond. The metal can be Li, Na, Mg, Cu, Pd or any opposite transitional metal. In this research lab we used Mg as our metallic portion of the organometallic compound. Organometallic compounds be special in that they intellect Carbon to become a nucleophile. More specifi wawly in this lab we used R-Mg-Br an alkyl radical magnesium halide to project the nucleophillic properties onto the Carbon atom, known as a Grignard reagent because of it founder chemist succeeder Grignard. The purpose of Grignard reactions is to create a C-C bond, more specifically a tertiary or a secondary alcohol. The Grignard reagents are unremarkably created with the solvents anhydrous diethyl divinyl ether or THF and are very var. sensitive. The Grignard reagent are very introductory which make them very unspoiled proton acceptors. In our experiment we created a tertiary alcohol by using an ester and carbonyl molecule.

The ester is converted to a ketone than immediately reacts with the Grignard reagent to reach the tertiary alcohol, triphenylmethanol. Reaction form Procedure A. Preparation of the Grignard reagent * Weigh somewhat .5 g of Magnesium turnings * reside mortar and pastel to fag turnings * Put tunings into a cycle layabout flask * Assemble apparatus * stool 2.4 mL of bromobenzene in 5 mL of anhydrous diethyl ether * Swirl mixture, than add 5mL to round bottom flask * Reflux reaction * Add .5 mL increments of the aeriform solution over 10 minutes B. Synthesis of Triphenylmethanol * Dissolve 1.2 mL of methyl benzoate in 5 mL of anhydrous diethyl ether *...If you call for to get a full(a) essay, order it on our website: Ordercustompaper.com

If you want to get a full essay, wisit our page: write my paper